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In a comparative clinical trial in patients with asthma who were not controlled on high dosages of inhaled corticosteroids, salmeterol/fluticasone inhalation aerosol salmeterol 42 mcg/fluticasone propionate 460 mcg free advair trial daily produced greater or similar improvement in morning PEFR than fluticasone inhalation aerosol 440 mcg twice daily with CFC propellants no freer advair trial commercially available in the US or salmeterol/fluticasone inhalation powder 50 mcg of salmeterol and 500 mcg of fluticasone propionate free advair trial daily respectively.If paradoxical bronchospasm occurs following dosing with Advair HFA, it should be treated immediately with an inhaled, short-acting bronchodilator; Advair HFA should be discontinued immediately; and alternative therapy should be instituted.
Upper airway symptoms of laryngeal spasm, irritation, or swelling, such as stridor and choking, have been reported in patients receiving Advair HFA. Immediate hypersensitivity reactions e.
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exceeding 176 but not more than 352 mcg of fluticasone propionateor its equivalentdaily via a metered dose inhaler In infants and children 4 years of age or younger with moderate persistent asthma that is not controlled by a low dosage of an inhaled corticosteroid, the only preferred option is to increase the maintenance dosage of the inhaled corticosteroid to a medium dosage e.
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