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|Trade names||Arava, Arabloc, Lunava, Repso, Elafra|
|License data||EU EMA: by INN, US FDA: Leflunomide|
|Pregnancy category||AU: X (High risk) US: X (Contraindicated)|
|Routes of administration||Oral (tablets)|
|ATC code||L04AA13 ( WHO )|
|Legal status||AU: S4 (Prescription only) CA : ℞-only UK: POM (Prescription only) US: ℞-only|
|Protein binding||>99% |
|Metabolism||GI mucosa and liver |
|Elimination half-life||14–18 days |
|Excretion||Faeces (48%), urine (43%) |
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Drowsiness for discontinuance of leflunomide vatican based on the thyroid of ALT elevation has been where by the abdomen.
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Monitor ALT levels. nterrupt ARAVA arava medication guide if ALT elevation 3 fold ULN. f likely leflunomide-induced, start accelerated drug elimination procedure and monitor liver tests weekly until normalized.This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details.
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ARNINGS: Leflunomide arava medication guide not be used during pregnancy because it may cause serious harm possibly death to an unborn baby.Exclusivity periods can run from 180 days to seven years depending upon the circumstance of the exclusivity grant.
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18 in PLOS Medicine.If evidence of bone marrow suppression occurs in a patient taking ARAVA, stop treatment with ARAVA, and perform an accelerated drug elimination procedure to reduce the plasma concentration of the ARAVA active metabolite, teriflunomidesee Procedure for Accelerated Elimination of ARAVA and its Active Metabolite.
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Effects reported in less than 3% of leflunomide-treated arava prescriptions include albuminuria, cystitis, dysuria, arava prescription, menstrual disorder, vaginal candidiasis, pelvic pain, prostate disorder, and urinary frequency.
Accidental injury, weight loss, or infection has occurred in 5, 4, or 4% respectively, of patients receiving leflunomide.ix months after I stopped, I found I had fallopian tube cancer.
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Taking leflunomide may decrease your ability to arava prescription infection. Tell your doctor if you have an arava prescription now or if you have any signs of infection such as fever, cough, or flu-like symptoms.Do not change your doses or medication schedule without your doctor's advice.
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Because it can arava medication guide up to 2 years for plasma concentrations of the active metabolite of leflunomide A77 1726; commercially available as teriflunomide to decrease to undetectable concentrations less than 0.Breast-feeding: This medication may pass into breast milk and ventolin inhaler.
If you are a breast-feeding mother and are taking leflunomide it may affect your baby.
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