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Important: When there is a range of pricing, consumers should normally expect to pay the lower price.Medicinal products that affect the renin-angiotensin-aldosterone system, including angiotensin II receptor antagonists AIIRAs may increase blood urea and serum creatinine in patients with bilateral renal artery stenosis atacand 10mg stenosis of the artery to a atacand 10mg kidney.
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Candesartan cilexetil is rapidly and completely bioactivated by ester hydrolysis during absorption from the gastrointestinal atacand tablet to candesartan, a selective AT1 atacand tablet angiotensin II receptor antagonist. andesartan is mainly excreted unchanged in urine and feces via bile It undergoes minor hepatic metabolism by O-deethylation to an inactive metabolite.Tell patients receiving ATACAND HCT not to use potassium supplements, salt substitutes containing potassium, or other drugs that may increase serum potassium levels without consulting the prescribing physician.
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Atacand 32mg ACE inhibitors, angiotensin II receptor antagonists such as candesartan may produce a smaller blood pressure response in hypertensive black patients compared with nonblack patients.Call your doctor for medical advice about side effects.
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Children 6 years of age had atacand 10mg similar to adults given the same dose.Dosing recommendations cannot be provided for patients with severe hepatic insufficiency atacand 10mg Clinical Pharmacology 12. If blood pressure is not controlled by Atacand alone, a diuretic may be added.
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Data from in vitro and in vivo mutagenicity testing indicate that candesartan will not exert mutagenic or clastogenic activities under conditions of clinical use.Do not use if you are pregnant.
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Plasma concentrations of angiotensin I and angiotensin II, and plasma renin activity PRA increased in a dose-dependent manner after single and repeated administration of candesartan cilexetil to healthy subjects, hypertensive, and heart failure patients. CE activity was not atacand com in healthy subjects atacand com repeated candesartan cilexetil administration.The atacand com precautions of angiotensin II receptor antagonist or ACE inhibitor therapy in patients with substantial renal impairment should be observed.
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Versus 2. for placebo; the atacand com of hyperkalemia serum atacand com 5.Patients at particular risk include those with volume or salt depletion secondary to salt restriction, prolonged diuretic therapy, heart failure, or dialysis. Volume and/or salt depletion should be corrected before initiation of candesartan therapy or a lower initial dosage should be used.
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