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No overall differences in safety or effectiveness have combigan gotas oftalmicas observed between elderly and younger patients. The following adverse reactions have been identified during use of PRED FORTE.The increase in mean IOP was seen with each treatment cycle, and the mean IOP generally returned to baseline between treatment cycles at the end of combigan gotas oftalmicas 6-month period Adverse reactions reported by greater than 2% of patients in the first 6 months following injection of OZURDEX for retinal vein occlusion and posterior segment uveitis include: intraocular pressure increased 25% conjunctival hemorrhage 22% eye pain 8% conjunctival hyperemia 7% ocular hypertension 5% cataract 5% vitreous detachment 2% and headache 4% Increased IOP with OZURDEX peaked at approximately week 8.
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Pregnancy: Prednisolone has been shown to be teratogenic in mice when given in doses 1-10 times the human dose. Dexamethasone, hydrocortisone, and prednisolone were ocularly applied to both eyes of pregnant mice five times per day on days 10 through 13 of gestation.propranolol certain antidepressants SSRIs such as fluoxetine, tricyclics such as amitriptyline digoxin, epinephrine, fingolimod, high blood pressure medications e.
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