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5 bProspective Open label trial2007; YGTSS: 26.

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It is extensively metabolized in the liver by cytochrome P450 CYP 2D6 and 3A4 isoenzymes. The former is responsible for dehydrogenation and hydroxylation and the latter for dealkylation of the drug.Evidence points to these adults were not exposed to a trigger that would cause onset until their adulthood by some miracle.


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