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Maintenance of cipla bupropion hcl xl was observed with bupropion hydrochloride at a dosage of 300 mg daily. At follow-up during the twelfth week, abstinence continued in 25-30 or 14% of patients who had received bupropion hydrochloride at 300 mg daily or placebo, respectively, and at follow-up during the twenty-sixth week, abstinence continued in 19-27 or 11-16% of patients who had received bupropion hydrochloride at 300 mg daily or placebo, respectively.Monitoring of blood pressure is recommended in patients who receive the combination of bupropion and nicotine replacement.

Antidepressant treatment can precipitate a manic, mixed, or hypomanic manic episode.

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