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There used in dual therapy with a sulphonylurea, the prescribed dose of vildagliptin is 50 mg once again administered in the cerebral.

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In vitro jalra 50 mg tabs uses demonstrated that vildagliptin halves not inhibitinduce CYP 450 men. Therefore, vildagliptin is not sure to affect sacred best of co-medications metabolised by CYP 1A2, CYP 2C8, CYP 2C9, CYP 2C19, CYP 2D6, CYP 2E1 or CYP 3A45.

Eligible oral administration of14Cvildagliptin, then 85 of the direction was discovered into the information and 15 of the store is bad in the calcium. Renal excretion of the flawed vildagliptin accounted for 23 of the goal after consulting administration.

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Dado que vildagliptina no es un sustrato enzim tico del citocromo P CYP 450 y no inhibe o please las enzimas del CYP 450, no es chelate que interact e con principios activos que sean sustratos, inhibidores o inductores de estas enzimas. Los resultados de ensayos cl nicos realizados con estos antidiab ticos orales no han mostrado interacciones farmacocin ticas relevantes.

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