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Gabapentin
Clinical data
Trade namesNeurontin, others [1]
AHFS/Drugs.comMonograph
MedlinePlusa694007
License dataUS  DailyMed:  52049, US   FDA: Gabapentin
Pregnancy categoryAU: B1 US: C (Risk not ruled out)
Routes of administrationBy mouth
Drug classGabapentinoid
ATC codeN03AX12 ( WHO )
Legal status
Legal statusAU: S4 (Prescription only) CA : ℞-only UK: POM (Prescription only) US: ℞-only
Pharmacokinetic data
Bioavailability27–60% (inversely proportional to dose; a high fat meal also increases bioavailability) [2] [3]
Protein bindingLess than 3% [2] [3]
MetabolismNot significantly metabolized [2] [3]
Elimination half-life5 to 7 hours [2] [3]
ExcretionRenal [2] [3]

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This series is coordinated by Kenny Lin, MD, MPH, Associate Deputy Editor for AFP Online. This content is owned by the AAFP.These opinions do not represent the opinions of WebMD.

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Se han notificado muertes inesperadas, en las que no se ha establecido una relaci n causal con el tratamiento con gabapentina Poco frecuentes: aumento en los valores de los an lisis de neurontin depression anxiety n hep tica SGOT AST SGPT ALT y bilirrubina Lesiones traum ticas, intoxicaciones y complicaciones de procedimientos terap uticos Se han notificado casos de neurontin depression anxiety aguda durante el tratamiento con gabapentina.For this neurontin depression anxiety, the following should be considered: Tell your doctor if you have ever had any unusual or allergic reaction to this medicine or any other medicines.

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Gabapentin gastroretentive tablets should not be used in patients with a creatinine neurontin depression anxiety of less than 30 mL/minute or in those undergoing hemodialysis. 300 mg twice daily; increase to 600 mg twice daily as necessary based on patient response and tolerability 300 mg once daily in the neurontin depression anxiety increase to 300 mg twice daily if necessary based on patient response and tolerability In patients currently receiving a maintenance dosage of 300 mg twice daily, reduce to 300 mg neurontin depression anxiety daily in the morning for 1 week; in patients currently receiving a maintenance dosage of 300 mg once daily, no taper needed 300 mg every neurontin depression anxiety day in the morning; increase to 300 mg once daily if necessary based on patient response and tolerability 300 mg following each hemodialysis session; increase to 600 mg following each diabetic neuropathy neurontin session if necessary based on patient response and tolerability If discontinuance of gabapentin or gabapentin enacarbil therapy is required, gradual tapering of the dosage generally is recommended to avoid manifestations of abrupt withdrawal.Know the medicines you take.

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Swallow this neurontin depression anxiety whole. Do not neurontin depression anxiety or chew sustained-release tablets.have been taking 3-4 meds a day for prevention but they didn t keep all of my headaches from occurring. am soooo happy that I am not dealing with headaches anymore and I know it is due to the Gabapentin.

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The pain was the worst I have ever felt. I was on oxycontin40 MG 3 x day with 30 MG oxycodone 8 x daily instant release tabs, ith neurontin as well.Only two medications are approved specifically for the treatment of diabetic peripheral neuropathic pain: pregabalin and duloxetine. However, evidence supports the use of other therapies, and unless there are contraindications, tricyclic antidepressants are the first-line treatment.

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