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|Trade names||Sinequan, Quitaxon, Aponal, others |
|License data||US FDA: Doxepin|
|Pregnancy category||AU: C US: B (No risk in non-human studies)|
|Routes of administration||By mouth, topical, intravenous, intramuscular injection |
|Drug class||Tricyclic antidepressant (TCA)|
|ATC code||D04AX01 ( WHO ) N06AA12 ( WHO )|
|Legal status||AU: S4 (Prescription only) CA : ℞-only UK: POM (Prescription only) US: ℞-only|
|Bioavailability||13–45% (mean 29%)  |
|Protein binding||76% |
|Metabolism||Hepatic (CYP2D6, CYP2C19)  |
|Metabolites||Nordoxepin, glucuronide conjugates |
|Elimination half-life||Doxepin: 8–24 hours (mean 17 hours)  Nordoxepin: 31 hours |
|Excretion||Urine: ~50%   Feces: minor |
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