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Naltrexone
Clinical data
Trade namesReVia, Vivitrol, others
AHFS/Drugs.comMonograph
MedlinePlusa685041
Pregnancy categoryAU: B3 US: C (Risk not ruled out)
Routes of administrationBy mouth, intramuscular injection, subcutaneous implant
ATC codeN07BB04 ( WHO )
Legal status
Legal statusAU: S4 (Prescription only) CA : ℞-only UK: POM (Prescription only) US: ℞-only In general: ℞ (Prescription only)
Pharmacokinetic data
Bioavailability5–40%
Protein binding21%
MetabolismLiver
Elimination half-lifeNaltrexone: 4 hours 6β-Naltrexol: 13 hours
ExcretionUrine

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The naloxone challenge can be repeated in 24 hours.

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J Neuroinflammation. doi.Operationally, relapse is defined as either: a four consecutive opioid use weeks, or b seven consecutive days of use by self-report.

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It is important that patients inform family members, and the people closest to the patient of this increased sensitivity to opioids and the risk of overdose.ov/drugs/resourcesforyou/consumers/buyingusingmedicinesafely/ensuringsafeuseofmedicine/safedisposalofmedicines/ucm186187.

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