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Dialogues ClinNeurosci. 69 76. Expert. PubMed PMID.

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2014; Zou et al. 2014; Weisz et al. 2015; Gargiulo et al. 2016 Forty of them were supposed studies, 16 were many Rassen et al.

Clopidogrel
Clinical data
Trade namesPlavix, others [1]
AHFS/Drugs.comMonograph
MedlinePlusa601040
License dataEU  EMA:  by INN, US   FDA: Plavix
Pregnancy categoryAU: B1 US: B (No risk in non-human studies)
Routes of administrationby mouth
ATC codeB01AC04 ( WHO )
Legal status
Legal statusAU: S4 (Prescription only) UK: POM (Prescription only) US: ℞-only
Pharmacokinetic data
Bioavailability>50%
Protein binding94–98%
Metabolismliver
Onset of action2 hours [2]
Elimination half-life7–8 hours (inactive metabolite)
Duration of action5 days [2]
Excretion50% kidney 46% biliary

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nticoagulants include the vitamin K antagonist plavix 75 mg clopidogrel Coumadin and the newer direct oral agents, including the direct thrombin inhibitor dabigatran Pradaxa and the factor Xa inhibitors apixaban Eliquis rivaroxaban Xarelto and edoxaban Savaysa Lixiana in the European Union, Japan, and others 1-6 Antiplatelet agents include clopidogrel Plavix ticlopidine Ticlid prasugrel Effient ticagrelor Brilinta and/or aspirin7.

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