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Dialogues ClinNeurosci. 69 76. Expert. PubMed PMID.
2014; Zou et al. 2014; Weisz et al. 2015; Gargiulo et al. 2016 Forty of them were supposed studies, 16 were many Rassen et al.
|Trade names||Plavix, others |
|License data||EU EMA: by INN, US FDA: Plavix|
|Pregnancy category||AU: B1 US: B (No risk in non-human studies)|
|Routes of administration||by mouth|
|ATC code||B01AC04 ( WHO )|
|Legal status||AU: S4 (Prescription only) UK: POM (Prescription only) US: ℞-only|
|Onset of action||2 hours |
|Elimination half-life||7–8 hours (inactive metabolite)|
|Duration of action||5 days |
|Excretion||50% kidney 46% biliary|
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Bleeding): aspirin + clopidogrel (1B). Warfarin: Target INR 2.5 (range 2-3). Aspirin : 75-325 mg daily. ACCP = American College of Chest ...:
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nticoagulants include the vitamin K antagonist plavix 75 mg clopidogrel Coumadin and the newer direct oral agents, including the direct thrombin inhibitor dabigatran Pradaxa and the factor Xa inhibitors apixaban Eliquis rivaroxaban Xarelto and edoxaban Savaysa Lixiana in the European Union, Japan, and others 1-6 Antiplatelet agents include clopidogrel Plavix ticlopidine Ticlid prasugrel Effient ticagrelor Brilinta and/or aspirin7.
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Consider use of another platelet P2Y12 inhibitor in patients identified as CYP2C19 poor metabolizers. Clopidogrel is indicated to reduce the rate of myocardial infarction MI and stroke in patients with non-ST-segment elevation ACSunstable angina UA plavix 75 mg clopidogrel myocardial infarction NSTEMI including patients who are to be managed medically and those who are to be managed with coronary revascularization.The concomitant administration of medicinal products associated with bleeding risk should be undertaken with caution plavix 75 mg clopidogrel section 4.
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